Eating Control
There is significant evidence that Zotrim helps you to both eat less during meals and to snack less between meals. Our feeling of fullness (satiety) is controlled by links between the brain, nervous system and gastrointestinal tract.
This includes 'satiety' signals that indicate when we have eaten enough and should stop eating. For example, a hormone called cholecystokinin (CCK) is released into the blood as food is digested, acts on receptors in the brain, which then slows the rate of stomach emptying.
The initial evidence for an effect of Zotrim was on slowing the rate of stomach emptying. Using ultrasound studies with 7 subjects who drank 400 ml apple juice, the stomach emptied much more slowly (average 58 minutes) after taking one dose of Zotrim compared to then taking a placebo tablet (emptying in 38 minutes).
This indicated that Zotrim, by slowing the rate of stomach emptying, should make us feel fuller longer and stop snacking between meals. This was supported by a study with 20 subjects, 10 of which took Zotrim and 10 of which took placebo for 20 days5. In the last week they were asked to record time to fullness during meals.
Perception of fullness occurred much sooner when taking Zotrim, for example, at lunch the average time to perceived fullness was decreased from 21.5 minutes to 12 minutes!
In the latest study with healthcare nurses, between meal snacking and attitude to fullness and hunger was monitored. It was found that:
- Between-meal snacking decreases (by a half) from the start of the study compared to six weeks of Zotrim use
- From 1.15 to 0.72 mid afternoon
- From 1.84 to 0.69 in evening
When taking Zotrim less than 20% reported that they "did not feel full unless they had eaten a large portion" compared with over 60% at the start of the study.
Between meal hunger ratings reduced from a high rating of 5 at the start of the study to medium 3 when taking Zotrim and increased again when Zotrim was stopped.
Zotrim contains a special combination of extracts from three South American plants that have a long history of use in foods for wellbeing and weight loss. The formulation was developed and optimised through extensive research and testing by an international team of medical researchers.
