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Ephedra is an evergreen shrub-like plant native to Central Asia and Mongolia. The principal active ingredient, ephedrine, is a compound that can powerfully stimulate the nervous system and heart.

Common Names -- ephedra, Chinese ephedra, ma huang

• Ephedra has been used for more than 5,000 years in China and India to treat conditions such as colds, fever, flu, headaches, asthma, wheezing, and nasal congestion.
• It has also been an ingredient in many dietary supplements used for weight loss, increased energy, and enhanced athletic performance.

The dried stems and leaves of the plant are used to create capsules, tablets, extracts, tinctures, and teas.

• An NCCAM-funded study that analyzed phone calls to poison control centers found a higher rate of side effects from ephedra, compared with other herbal products.
• Other studies and systematic reviews have found an increased risk of heart, psychiatric, and gastrointestinal problems, as well as high blood pressure and stroke, with ephedra use.
• According to the FDA, there is little evidence of ephedra's effectiveness, except for short-term weight loss. However, the increased risk of heart problems and stroke outweighs any benefits.

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