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Glycine Foods

Triggers Needed Oxygen

Glycine helps trigger the release of oxygen to the energy requiring cell-making process; important in the manufacturing of hormones responsible for a strong immune system.

Although most glycine is found in proteins, free glycine is found in body fluids as well as in plants. It is present in considerable amounts in prostate fluid.

The normal diet contributes approximately 2 grams of glycine daily.

Glycine is found in many foods high in protein, such as fish, meat, beans, and dairy.

Glycine: Non Essential Amino Acid

Glycine is a non-essential amino acid and has the simplest structure of all amino acids. It to fits easily within protein chains and makes space for structurally larger amino acids. This feature makes it very important for specific bodily functions.

Glycine is also a precursor of creatine, which is used to construct DNA and RNA. And it supports glycogen storage, thereby making more glucose available for energy production.

Glycine Encephalopathy

What is glycine encephalopathy?
Glycine encephalopathy (also known as nonketotic hyperglycinemia or NKH) is a genetic disorder characterized by abnormally high levels of a molecule called glycine. This molecule is an amino acid, which is a building block of proteins.

Glycine also acts as a neurotransmitter, which is a chemical messenger that transmits signals in the brain.

Glycine encephalopathy is caused by the shortage of an enzyme that normally breaks down glycine in the body. A lack of this enzyme allows excess glycine to build up in tissues and organs, particularly the brain, leading to serious medical problems.

The most common form of glycine encephalopathy, called the classical type, appears shortly after birth. Affected infants experience a progressive lack of energy (lethargy), feeding difficulties, weak muscle tone (hypotonia), abnormal jerking movements, and life-threatening problems with breathing.

Most children who survive these early signs and symptoms develop profound intellectual disability and seizures that are difficult to treat.

For unknown reasons, affected males are more likely to survive and have less severe developmental problems than affected females. (Source: Genetics Home Reference)

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