Histidine has been used in the treatment of rheumatoid arthritis, allergic diseases, ulcers and anemia. A deficiency can cause poor hearing.
Histidine is also a precursor of histamine, a compound released by immune system cells during an allergic reaction.
What is Histidine Needed For?
Histidine is needed for growth and for the repair of tissue, as well as the maintenance of the myelin sheaths that act as protector for nerve cells. It is further required for the manufacture of both red and white blood cells, and helps to protect the body from damage caused by radiation and in removing heavy metals from the body.
In the stomach, histidine is also helpful in producing gastric juices, and people with a shortage of gastric juices or suffering from indigestion, may also benefit from this nutrient.
Histidine is also the main precursor for histamine, which is an important chemical in the human immune system. Histamine is important in other areas as well. For example, sexual arousal is influenced by histamine. Sexual arousal, pleasure and libido in general may be improved by consuming supplemental histidine, along with supplements of the vitamins B3 (niacin) and the vitamin B6.
Some people take 1,000 mg of histidine two to three times per day in capsule or tablet form but it is best to work out the dosage requirements as 8 to 10 mg per day per kilogram of body weight.
There are no reported side effects with histidine, but too high levels of histidine may lead to stress and mental disorders such as anxiety. People with schizophrenia have been found to have high levels of histidine. People suffering from schizophrenia or bipolar (manic) depression should not take a histidine supplement without the approval of their medical professional.
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